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KMID : 0032220080200030107
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Annals of Dermatology
2008 Volume.20 No. 3 p.107 ~ p.112
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Targeted Broadband UVB Phototherapy for the Treatment of Localized Vitiligo
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Kim Jeong-Eun
Ahn Hyo-Hyun
Kye Young-Chul
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Abstract
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Background: Several new treatments appear to have higher success rates than previous therapies for the treatment of vitiligo, and targeted phototherapy is an alternative that may prove to be time-efficient and an effective therapeutic option for the management of this condition.
Objective: The aim of this study was to evaluate the efficacy of targeted broadband UVB phototherapy for the treatment of localized vitiligo.
Methods: Fifty-three vitiliginous patches on thirty-five patients (16 males, 19 females) were treated using a targeted broadband UVB phototherapy device. Treatment was started at 70% of the minimal erythema dose, and then gradually increased. Lesions were treated twice a week for a maximum of 60 treatment sessions.
Results: Subjects tolerated treatment well. Forty-one of the fifty-three patches (77.4%) achieved repigmentation on > or =75% of the treated areas. Best results were obtained on the face and neck; 20 of the 24 patches (83.3%) concerned achieved > or =75% repigmentation. The least response was on the hands and feet; 3 of 6 patches (50%) showed > or =75% repigmentation. The results were better for focal type than segmental type vitiligo.
Conclusion: Targeted broadband UVB phototherapy appears to be highly effective at restoring pigmentation in patients with localized vitiligo.
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KEYWORD
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Targeted broadband UVB phototherapy, Vitiligo
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